This article examines the impact of faith on the business approach of Christian entrepreneurs in developing and emerging market settings. Special attention is given to the distinctive context for business in these environments (including high levels of poverty and corruption); the entrepreneurs’ responses, and how faith influences these responses. Focusing on the experience of two entrepreneurs out of a larger pool of 65, we found that faith appears to play an important role in shaping their priorities. Putting reputation before short-term profit, both entrepreneurs adopted a zero-tolerance policy towards corrupt dealing, and have become known for this stance. Both entrepreneurs also exhibit a sense of dependence on God that is greater than that documented amongst Christian entrepreneurs in developed countries, perhaps reflecting the challenges associated with their environments.